Antigen-Presenting Cells (APCs) like dendritic cells, macrophages, and B cells activate T cells by processing foreign pathogens into peptide fragments, displaying them on their surface bound to Major Histocompatibility Complex (MHC) molecules (Signal 1), and providing co-stimulatory signals (Signal 2). This dual signaling through the T Cell Receptor (TCR) binding the peptide-MHC complex and co-stimulatory molecules (like B7 on APCs binding CD28 on T cells) triggers T cell proliferation and diffe
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. . . . Antigen-presenting cell (APC) refers to the ability of certain cells, including macrophages, dendritic cells, and B lymphocytes to take up, process, and present antigenic peptides to naive CD4 T cells in the context of major histocompatibility complex class II (MHC class II) and co-stimulatory molecules #microbiology #microbiologist #microbiologylab #explorepage #microbe #science #molecularbiology #kesfet #virology #immunology #phd #phdstudent | Medical Microbiologist
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