BRAF is a human gene that encodes a protein called B-Raf. The gene is also referred to as proto-oncogene B-Raf and v-Raf murine sarcoma viral oncogene homolog B, while the protein is more …

BRAF gene mutations can cause normal cells to become cancerous. Learn about the mutation, the types of cancer it can cause and the treatments available.

Apr 16, 2024 · In this review, we cover the current understanding of BRAF mutations and associated clinical characteristics in patients with metastatic NSCLC, approved and emerging treatment options, …

Sep 15, 2025 · BRAF mutations are present in many melanomas as well as some lung cancers, colon cancers, and more. Learn about the basics, testing, and treatment.

The BRAF gene provides instructions for making a protein that helps transmit chemical signals from outside the cell to the cell's nucleus. Learn about this gene and related health conditions.

6 days ago · The BRAF gene and its corresponding protein are central to cancer research and treatment today. The gene belongs to a class of proto-oncogenes, which are involved in cell growth and …

Nov 13, 2025 · BRAF (B-Raf Proto-Oncogene, Serine/Threonine Kinase) is a Protein Coding gene. Diseases associated with BRAF include Lung Cancer and Cardiofaciocutaneous Syndrome 1. …

With the identification of activating mutations in BRAF across a wide variety of malignancies, substantial effort was placed in designing safe and effective therapeutic strategies to target BRAF.

May 30, 2025 · First-line treatment with encorafenib plus cetuximab (EC) with or without chemotherapy (oxaliplatin, leucovorin, and fluorouracil [mFOLFOX6]) for BRAF V600E–mutated metastatic …

3 days ago · Targeted inhibition of mutant BRAF has transformed the management of BRAF-V600–mutant melanoma and other malignancies, with multiple ATP-competitive kinase inhibitors …