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  1. Tissue factor - Wikipedia

    The F3 gene encodes tissue factor also known as coagulation factor III, which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it …

  2. Tissue Factor Structure and Function - PMC

    Tissue factor (TF) is an integral membrane protein that is essential to life. It is a component of the factor VIIa-TF complex enzyme and plays a primary role in both normal hemostasis and …

  3. Tissue Factor - an overview | ScienceDirect Topics

    Tissue factor, an integral membrane protein, is the essential protein cofactor for factor VIIa. Binding to tissue factor enhances the enzymatic activity of factor VIIa many thousand-fold.

  4. Tissue factor – Knowledge and References – Taylor & Francis

    Tissue factor is a transmembrane glycoprotein that is expressed by subendothelial fibroblast-like cells surrounding blood vessels. It is a central factor in regulating clotting mechanisms and …

  5. Exploring Tissue Factor and Factor 3 Roles in Disease

    Factor 3, known as tissue factor in the context of the extrinsic pathway of coagulation, is often the starting point for the coagulation cascade. When tissue factor interacts with factor VII, it forms …

  6. Tissue Factor, Blood Coagulation, and Beyond: An Overview

    Tissue factor (TF), also known as factor III, essentially provides additional protection to vital organs prone to mechanical injury; its strategic location is considered as a hemostatic …

  7. Molecule of the Month: Tissue Factor - RCSB: PDB-101

    Tissue factor starts a cascade of interactions that lead to formation of a clot. The first step occurs when factor VII, which is found in the blood, binds to tissue factor.

  8. Normal and Abnormal Functions of Tissue Factor. A Review Graciela Krikun YALE School of Medicine, Department of OB-GYN and reproductive sciences, USA

  9. Tissue Factor, Blood Coagulation, and Beyond: An Overview

    Emerging evidence shows a broad spectrum of biological functions of tissue factor (TF). TF classical role in initiating the extrinsic blood coagulation and its direct thrombotic action in …

  10. Tissue factor Definition - Anatomy and Physiology I Key Term

    Tissue Factor is a protein found on the surface of cells that initiates blood clotting by activating the coagulation cascade. It plays a crucial role in hemostasis by binding with factor VIIa, which …