Background: Liver hepatocellular carcinoma (LIHC) is a leading cause of cancer-related mortality, with an immunosuppressive tumor microenvironment (TME) contributing to therapeutic resistance.

The original version of this story appeared in Quanta Magazine. If you want to solve a tricky problem, it often helps to get organized. You might, for example, break the problem into pieces and tackle ...

This valuable study presents a mouse gastruloid system to generate successive waves of hematopoietic progenitors that in vivo would emerge during embryonic development. Although this newly revised ...

Background: Immunotherapy has been used in the clinical management of TNBC. While BRCA1 mutations are associated with immunotherapy response, the therapeutic outcomes in TNBC patients are not ...

There is a new sorting algorithm a deterministic O(m log2/3 n)-time algorithm for single-source shortest paths (SSSP) on directed graphs with real non-negative edge weights in the comparison-addition ...

If you want to solve a tricky problem, it often helps to get organized. You might, for example, break the problem into pieces and tackle the easiest pieces first. But this kind of sorting has a cost.

Google’s June 2025 Core Update just finished. What’s notable is that while some say it was a big update, it didn’t feel disruptive, indicating that the changes may have been more subtle than game ...

Here’s a scary scenario: You’ve been put in charge of air traffic control at Newark airport near New York. You need to make sure every plane can taxi between the runway and its gate without hitting ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...