OpenAI's updated GPT-5.5 Instant is better at shopping, complex constraints, and understanding user intent — and it's already in the API

OpenAI is moving away from models that require heavy hand-holding and toward systems that can better infer the user’s goal, ...
Nature

Structural variant calling using Sniffles2

Structural variants (SVs) are the most common nucleotide alteration per human genome compared to other variant types and have profound implications in evolution, diseases and regulation of genes.
InfoQ

Ky 2.0 Fetch API Wrapper with Revamped Hooks, Smarter Timeouts, and Built-In Schema Validation

Ky 2.0 is an open-source JavaScript HTTP client built on the Fetch API, featuring significant updates such as consolidated ...
The Times of Israel

Trump confirms calling Netanyahu ‘f***ing crazy’ during their recent phone call

US President Donald Trump confirmed that he called Prime Minister Benjamin Netanyahu “fucking crazy” during a phone call on Monday about Israel’s conflict with Hezbollah, but added that he respects ...
247Sports.com

Halzle explains Vols' play-calling process, approach to scripting plays

Tennessee coach Josh Heupel has been involved in the Vols’ offensive play-calling since arriving in Knoxville almost three years ago. That hasn’t changed since first-year offensive coordinator Joey ...
MacStories

Early Impressions of Claude Opus 4 and Using Tools with Extended Thinking

For the past two days, I’ve been testing an early access version of Claude Opus 4, the latest model by Anthropic that was just announced today. You can read more about the model in the official blog ...