This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

On a sunny May afternoon 14 years ago, a group of doctors from across the country gathered in a windowless conference room at the US Food and Drug Administration’s main campus in White Oak, Maryland, ...

This article is the first in a series on prescription drug monitoring programs and analysis tools designed to give clinicians a view of how likely their patient is to abuse or overdose on a prescribed ...

C. Michael White does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond ...

Fentanyl, a synthetic opioid 50 times more potent than heroin, is cheaper to produce and easier to smuggle across borders, fueling the illicit opioid epidemic in the United States with devastating ...

The drug is for moderate to severe acute pain. The U.S. Food and Drug Administration (FDA) on Thursday approved a new type of prescription pain medication for adults to treat moderate to severe acute ...

For the first time in two decades, the Food and Drug Administration (FDA) has approved a new class of medication that provides an alternative to addictive opioids for patients looking to manage ...

Washington — Federal officials on Thursday approved a new type of pain drug designed to eliminate the risks of addiction and overdose associated with opioid medications like Vicodin and OxyContin. The ...

Rodin is a clinician scientist and assistant professor of geriatrics and palliative medicine at the Icahn School of Medicine at Mount Sinai. A woman sat in our emergency department in agonizing pain, ...

Weight-loss drugs like Wegovy and Zepbound are transforming the health of millions of people—and a new study hints that even more could benefit from the drugs’ other effects on the body. A study ...

Walmart reached a proposed settlement agreement about its distribution of prescribed opioids on Friday according to Security and Exchange Commission (SEC) filings. This settlement includes three ...