When the liver fails, toxins—such as ammonia—that should be filtered from the blood build up and reach the brain. The result ...
Shanghai researchers have mapped regulatory 'switches' in brain-supporting astrocytes, leading to the discovery of a gene that can halt Alzheimer's progression in mice. The gene, Ferd3l, restored near ...
When the liver fails, toxins – such as ammonia – that should be filtered from the blood build up and reach the brain. The result is hepatic encephalopathy (HE), a devastating neurological complication ...
Proxygen Expands Platform Beyond Degradation to Build Next-Generation Induced Proximity Therapeutics
Proxygen’s second lead candidate, CDK12, is a brain-penetrant glue degrader program designed to inactivate the transcriptional kinase CDK12, a target implicated in aggressive HER2-driven cancers and ...
Could you summarize the core thesis of your research regarding the ‘Cerebral Windkessel’ and how it redefines our ...
Scientists from Trinity College Dublin and RCSI University of Medicine and Health Sciences have created new "hybrid" immune ...
The quail is a small, unassuming bird that glides rather than flies and prefers to hide under bushes than to perch on top of ...
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Living better with chronic muscle pain
Chronic muscle pain can be exhausting, both physically and emotionally, but science is uncovering new ways to understand and manage it. From identifying unique pain pathways to exploring innovative ...
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