When two defective gene variants combine, normal protein function can sometimes be restored.

Can the brain keep working when its architecture changes? Researchers at the University of Geneva (UNIGE) have discovered ...

A multidisciplinary team has developed a selective compound that inhibits an enzyme tied to inflammation in people at genetic ...

After three years of study, the researchers found that alpha-synuclein, a protein closely linked to Parkinson’s disease, forms an abnormal connection with an enzyme called ClpP. This enzyme normally ...

Houston hospitals say medical appointments and non-emergency services could be disrupted during the winter storm. Here's what ...

Dewpoint has selected a novel small molecule to prevent the formation of abnormal TDP-43 protein clumps in ALS and other ...

A treatment that restores normal kidney function in almost half of patients with lupus nephritis has been approved by the National Institute for Health and Care Excellence (NICE). Obinutuzumab ...

Neural tissue normally dies quickly without oxygen. Yet bird retinas—among the most energy-demanding tissues in the animal ...

Researchers have identified a key molecular interaction that accelerates Parkinson’s disease by damaging the brain’s energy ...

Roche's Gazyvaro, a drug that can restore kidney function in people living with lupus nephritis, has been cleared for use by ...

NICE has recommended obinutuzumab with mycophenolate for severe lupus nephritis after trials showed higher renal response and fewer flares.

A Vitamin A byproduct could weaken the immune system's cancer-fighting ability, according to new Princeton University ...