In mammalian cells, the nucleolus is the central site for ribosome biogenesis. It is composed of distinct subcompartments: the fibrillar center (FC), the dense fibrillar component (DFC), the periphery ...
The primary function of the nucleolus is as the site of ribosome-subunit biogenesis in eukaryotic cells. The initial ribosomal RNA (rRNA) precursor is transcribed by RNA polymerase I and is ...
This is a preview. Log in through your library . Abstract To understand how nuclear machineries are targeted to accurate locations during nuclear assembly, we investigated the pathway of the ribosomal ...
This is a preview. Log in through your library . Abstract The four nucleolar proteins NOP1, SSB1, GAR1, and NSR1 of Saccharomyces cerevisiae share a repetitive domain composed of repeat units rich in ...
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