Single-cell sequencing provides unprecedented detail into cell-to-cell variability, uncovering key biological mechanisms in ...

(L to R) Co-first authors Peipei Zhou, Ph.D., Hao Shi, Ph.D. and corresponding author Hongbo Chi, Ph.D., all of the St. Jude Department of Immunology. T cells are used in adoptive cell therapy (ACT) ...

The gene editing tool known as CRISPR-Cas9 is changing what's possible for treating a wide range of diseases caused by ...

In the past decade there has been significant interest in studying the expression of our genetic code down to the level of single cells, to identify the functions and activities of any cell through ...

The use of induced pluripotent stem cells (iPSCs) has led to a paradigm shift in cellular immunotherapy. By reprogramming somatic cells into a pluripotent state, iPSCs represent a renewable source of ...