The biggest loser in this ACC title game scenario is Miami (10–2), ranked No. 12 in both the latest CFP rankings and the AP Top 25. The Hurricanes are arguably the ACC’s best shot at a national championship but likely will find themselves on the outside looking in at the 12-team CFP bracket, especially if Virginia wins the game.

Kickoff from Bank of America Stadium in Charlotte is at 8 p.m. ET. The Cavaliers are 4-point favorites in the latest Virginia vs. Duke odds, while the over/under is 57.5. Before making any Duke vs. Virginia picks, check out the college football predictions from the SportsLine Projection Model .

The Blue Devils could win the ACC despite having five losses. Meanwhile, Miami sits on the cusp of the College Football Playoff and will be forced to watch the conference title game on television.

No. 4 Duke plays the No. 7 Michigan State Spartans after Cameron Boozer scored 29 points in the Blue Devils' 67-66 win against the Florida Gators.

One of college football's great modern rivalries will take center stage on Saturday afternoon as No. 3 Georgia squares off against No. 9 Alabama in the SEC Championship Game. This will be the fifth time the Bulldogs and Crimson Tide have met in the SEC Championship Game (2012,