Dietary restriction reshapes CD8+ T cell metabolism by increasing ketone body–driven acetyl-CoA production, preventing ...

Dietary iron deficiency in mice alters lung T cell activation during influenza infection and leads to memory T cells that are ...

Novel, Potent, Selective and Orally Available DGKα Inhibitors for the Treatment of Tumors view more . Credit: Insilico ...

Selinexor-based regimens enhance T-cell activation in RRMM patients, without increasing inhibitory checkpoint molecules, indicating resistance is not due to T-cell exhaustion. Baseline protein ...

Hepatocellular carcinoma (HCC) is the sixth leading cause of cancer-related mortality worldwide.1 Despite therapeutic ...

Phase II Trial of Nivolumab Plus Doxorubicin, Vinblastine, Dacarbazine as Frontline Therapy in Older Adults With Hodgkin Lymphoma Colorectal cancer (CRC) remains a major global health burden, being ...

Murine data suggest dietary iron deficiency preserves influenza specific memory T cell numbers yet impairs cytokine effector ...

New research published in The Journal of Immunology suggests that a lack of dietary iron can negatively affect the ability of ...

Serious side effects, including neurotoxicity and intestinal inflammation, that appear weeks or months after patients receive ...

When a cell receives a message from outside, it generates a molecule called cyclic AMP (cAMP) to relay this message. To ...