RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...

At a virtual conference in November 2020, the winner of a biennial protein-structure-prediction challenge was announced: AlphaFold. Created by Google DeepMind, this computational tool had blown its ...

A research team at Florida State University's Institute of Molecular Biophysics and Department of Chemistry and Biochemistry ...

Researchers have used cryo-EM and computational tools to visualize ribozyme assembly, shedding light on life's most versatile ...

Certain guanine-rich regions of the transcriptome can fold up into four-stranded structures called RNA G-quadruplexes that are thought to have harmful effects in living cells. Both eukaryotes and ...

Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular ...

The nitrogen in the gum was found to be in nitrogen heterocycles, which are the building blocks of nucleobases in DNA and RNA ...

This is where the Nottingham team, led by Dr Aditi Borkar, Assistant Professor in Molecular Biochemistry & Biophysics in the School of Veterinary Medicine and Science, has achieved a transformative ...

This article explores how challenges such as sequence optimization, immune activation and off-target effects are being ...

A research team at the Institute of Molecular Biophysics and the Department of Chemistry and Biochemistry at Florida State ...

The chemical structure of uracil, showing its single-ring pyrimidine structure. Uracil forms hydrogen bonds with adenine in RNA, contributing to the molecule's structure and function. (Image: Public ...