This scanning electron microscopy image captures the moment where degranulating mast cells (pseudo-colored in sepia) attract and start to incorporate living neutrophils (pseudo-colored in cyan), ...

Mast cells are pivotal effectors in immune responses, acting as both sentinels and mediators in allergic and inflammatory processes. Their ability to rapidly degranulate and release a myriad of ...

The function of mast cells, which are part of the immune system, is still a mystery. Scientists have now shown in mice: mast cells function as a sensor that signals the animals to avoid antigens, ...

Although many topical or systemic antibiotics exist to treat acne vulgaris, the common inflammatory skin disease is not fully treatable. A new article published in The Journal of Clinical and ...

Eosinophils and mast cells are two types of immune cells with critical roles in responding to foreign assaults. When these cells do not function properly, several disease outcomes can develop (e.g.

– Data provide insights on the signaling pathways involved with AK006 mast cell inhibition –– AK006 has a distinct mechanism of action that leads to broad inhibitory effects on mast cells – The ...

For many patients with diverse and seemingly unrelated symptoms, obtaining an accurate diagnosis can take years of specialist visits and inconclusive tests. Mast cell activation syndrome, a disorder ...

Q: My doctor thinks my mast cells are activating inappropriately and may be causing many of the symptoms I periodically have. Please tell me more about this condition. A: Mast cells are an important ...

New research at WashU Medicine has found that histamine-releasing immune cells cause the gates to the brain to close when bacteria are detected, blocking fluid movement out of the brain and pathogen ...