Major histocompatibility complex class II (MHC-II) molecules play a critical, yet historically overlooked, role in tumor ...

The major histocompatibility complex class I (MHC-I) antigen presentation pathway is central to the adaptive immune response. In this process, intracellular proteins are degraded primarily by the ...

MHC class II molecules are central to the adaptive immune response, serving as the means by which antigen-presenting cells, notably dendritic cells, display processed peptides to CD4+ T cells. This ...

The Major Histocompatibility Complex region evolves via gene birth-and-death, resulting in short-lived genes, rapidly expanding gene subfamilies, and many gene fragments.

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 5 (February 1, 2022), pp. 1-3 (3 pages) C. Liu, Y. Zhang, C. C. Liu, D ...