Understanding how long non-coding RNAs (lncRNAs) regulate gene expression and genome structure remains a major challenge in ...

Although the function of most long noncoding RNA (lncRNA) genes remains a mystery, a subset is co-expressed in the brain along with neighboring genes that code for proteins involved in gene expression ...

Researchers from the University of Texas and University of Tennessee set out to determine if the long noncoding RNA (lncRNA) MALAT1 (metastasis associated lung adenocarcinoma transcript 1), which is ...

The vast non-coding portion of the human genome has had many names, including ‘junk’ and ‘dark matter.’ But research, including the international ENCODE project, has shown that these regions are ...

Northwestern Medicine investigators have discovered that a novel long noncoding RNA (lncRNA), which are usually 200 nucleotides longer than typical RNAs and are widely expressed in cells, could serve ...

Measurable Residual Disease and Fusion Partner Independently Predict Survival and Relapse Risk in Childhood KMT2A-Rearranged Acute Myeloid Leukemia: A Study by the International ...

When researchers look for potential cancer therapy targets, they typically go after protein-coding genes that participate in ...

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ...

Colorectal cancer (CRC) remains one of the most prevalent and deadly cancers worldwide, with rising incidence linked to dietary and lifestyle changes. Despite advances in surgery and chemotherapy, ...

Neurodegenerative diseases, such as Alzheimer's disease and dementia, are medical conditions that entail the progressive loss ...