Nobel laureate David Baker’s latest foundation model can design proteins that interact to any biomolecule for broad biotech applications.
The study presents a new mesoscopic (i.e., between microscopic and macroscopic) simulation model of DNA movement. This new model is essential to optimise research in the field of nucleic acids ...
In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...
AZoLifeSciences on MSN
Circular single-stranded DNA molecule can simultaneously silence multiple microRNAs
Professor Dongsheng Liu of Tsinghua University, Professor Ziyang Hao of Capital Medical University, and Researcher Yuanchen ...
Google DeepMind has expanded its AlphaFold AI system to not only predict the structure of proteins, but also to model how proteins interact with other cell structures, including DNA, RNA, and small ...
A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.
News-Medical.Net on MSN
DNA language model performance hinges on pre-training data choices
Researchers at The University of Texas MD Anderson Cancer Center have performed a comprehensive evaluation of five artificial intelligence (AI) models trained on genomic sequences, known as DNA ...
Morning Overview on MSN
DNA shape and stiffness steer key gene regulators
For decades, biologists treated DNA as a static string of letters, a linear code that cells read like text on a page. A new ...
MASPIN (“tumor suppressor shield”): MASPIN is a natural defense protein that blocks tumor invasion, regulates cell migration and angiogenesis, promotes apoptosis, and enhances treatment sensitivity.
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