Using single oligonucleotides, a variety of DNA cassettes for RNAi vectors were constructed in only few minutes in an automated manner. The cassettes, targeting the eGFP, were cloned into plasmids ...

These efforts have focused on vectors that are based on the genomes of adeno-associated viruses (AAVs). In collaboration with Hildegard Büning (Professor of the Infection Biology of Gene Transfer at ...

Strategies based on the use of gene therapy to mitigate the effects of mutations that cause blindness are undergoing rapid development. Novel gene vectors now achieve widespread gene delivery and ...

These efforts have focused on vectors that are based on the genomes of adeno-associated viruses (AAVs). In collaboration with Hildegard Büning (Professor of the Infection Biology of Gene Transfer at ...

The incidence of genetic mutations that result in rapid deterioration of the ability to see is larger than is generally supposed. For example, on the order of five million people around the world ...

The incidence of genetic mutations that result in rapid deterioration of the ability to see is larger than is generally supposed. For example, on the order of five million people around the world ...