T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...

In their new study, the LJI scientists are the first to show that GPR25 is induced by a signaling molecule called TGF-β.

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

Embryonic stem cells are powerful tools for understanding how organisms develop and how tissues regenerate. These cells have ...

Understanding how these cells develop and function is like decoding a complex puzzle. "By perfecting stem cell methods that mimic the development of the normal blood stem cells found in our bodies we ...

Using computer-designed proteins, researchers at the University of Washington (UW) School of Medicine have shown they can direct human stem cells to form new blood vessels in the lab. Their findings ...

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery. The process of how a humble single cell becomes an organism fascinates scientists across ...

Cancer research, drug safety testing and aging biology may all gain a major boost from a new fluorescent sensor developed at ...

For example, naïve T cells increase in size before undergoing a burst of proliferation, while liver and fat cells enlarge or contract in response to nutrient availability. In these cases, size changes ...

Researchers have published an atlas of zebrafish development, detailing the gene expression programs that are activated within nearly every cell type during the first five days of development, a ...