GAO Caixia's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has pioneered the use of artificial intelligence (AI)-assisted methods to discover novel ...

A study published last week presents a compact base editor that enables efficient in vivo delivery using a single adeno-associated virus (AAV) vector. The innovation, once approved in clinical trials, ...

CRISPR-Cas9’s ability to cut and edit DNA have long been the focus of the genome editing story. But CRISPR-Cas–guided base editors, that specifically correct a common class of base substitutions ...

A single mutation in a person’s genome can be the difference between health and disease, and with base editing, researchers can recreate these mutations in a laboratory to study how genetic changes ...

A form of CRISPR widely expected to be safer and possibly more effective that the original has aced its first substantive test. When CRISPR “base editing” was used to knock out two ...

The new base editing platform may help researchers understand and correct genetic diseases by selective editing of single DNA 'letters' across nucleobase classes. New genome-editing technologies ...

Even the best editor sometimes introduces typos. That’s true whether the editor is human or a version of the much-heralded gene-editing tool CRISPR. One type of CRISPR gene editor that changes ...