PanMAN data structures compress pangenomes massively, encode evolutionary histories, and enable scalable analysis of millions of genomes.
In mantle cell lymphoma (MCL), an aggressive form of B-cell non-Hodgkin lymphoma, TP53 mutations are known to affect patients’ prognosis—but questions remain. What does the heterogeneity of TP53 ...
Engineers at UC San Diego have developed a new data structure and compression technique that enables the field of pangenomics ...
Using sequencing instruments from multiple vendors, scientists from the University of Utah Health, the University of Washington, PacBio, and elsewhere have developed what they claim is the most ...
A study led by Aaron Hobbs, Ph.D., and Rachel Burge, Ph.D., at MUSC Hollings Cancer Center, reveals why a specific gene ...
A graph-based computational tool for detecting previously invisible genetic mutations has been developed. Researchers at the University of California, Los Angeles (UCLA; USA) and the University of ...
AZoLifeSciences on MSN
New pangenomic approach enables unprecedented scaling for genetic data
Researchers at the University of California have created a novel data structure and compression method that allows ...
Santhosh Girirajan receives funding from the National Institutes of Health. Genetic inheritance may sound straightforward: One gene causes one trait or a specific illness. When doctors use genetics, ...
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