This review explains how glucose scarcity, lipid disruption, amino acid deprivation, and toxic metabolites weaken CAR-T cells ...

The inflammatory tumor microenvironment (TME) is a complex network of cancer, immune, and stromal cells interacting through cytokines and growth factors to drive tumor growth, angiogenesis, and immune ...

Lung cancer treatment and outcomes are profoundly influenced by the tumor microenvironment (TME), particularly in resectable ...

Breast cancer is the most diagnosed cancer and the second leading cause of cancer-related mortality among women world-wide. Breast cancer is a heterogeneous ...

Cancer behaves as a complex, evolving system in which interactions between malignant cells and their surrounding environment shape growth, adaptation, and resistance to therapy. This understanding ...

Scientists have developed a way to turn the body's own immune cells into cancer-fighting agents—without removing them from ...

The stroma to tumor ratio potentially identifies higher risk bladder cancer tumors and might help guide immunotherapy. Bladder tumors with higher stromal content may have a more immunosuppressive ...

At AACR 2026, prominent cancer researchers discussed the latest advances in mitigating tumor evasion, targeting cancer ...

First Ascent Biomedical's Functional Precision Oncology bridges that gap by testing living tumor cells to generate actionable data in about 10 days, helping physicians choose the right treatment ...

New research shows that type I interferons produced during respiratory viral infections reshape the lung microenvironment, ...