The scope of human cell type atlases widened considerably today. Formerly, landscapes of individual cell types were largely confined to single organs. But now, thanks to four single-cell RNA ...

Genetic studies have revealed many genes linked to both common and rare disease, but to understand how those genes bring about disease and use those insights to help develop therapies, scientists need ...

Donna L. Farber is a professor of surgical sciences, microbiology and immunology at Columbia University Irving Medical Center in New York City, New York, USA. Early in the pandemic, my team spotted ...

Scientists at Duke-NUS Medical School have developed two powerful computational tools that could transform how researchers ...

Nucleic acid extraction from biological samples is inherently difficult to execute consistently across different tissue types. Some tissue matrices are fibrous, contained in protective cell walls, or ...

An international team of researchers reached a major milestone in decoding the human genome by linking genes across all chromosome of many individual people to specific tissues and disease processes.

“Expression tells us what cells do, but regulatory DNA tells us where they come from, how they develop, and which germ layer ...

Dissociating tissues into single cells is a core laboratory technique and vital for widely used applications such as next-generation sequencing or flow cytometry. Scientists who employ tissue ...

Our bodies are constantly breaking down. Over time, their built-in repair mechanisms also fail. Knee cartilage grinds away. Hip joints no longer support weight. Treatments for breast cancer and other ...

Tissue engineering is an interdisciplinary field that combines principles from engineering, biology, and materials science to develop biological substitutes that restore, maintain, or improve tissue ...