Heme binding to a bacterial transcription factor is critical for hydrogen sulfide (H₂S) signaling, report researchers from Japan. Heme binding promotes the reaction of H₂S with the transcription ...

A research team has uncovered a previously unknown type of immune signaling molecule—a novel compound combining histidine and ADP-ribose—produced by bacteria's Thoeris II defense system in response to ...

Light is a universal stimulus that influences all living things. Cycles of light and dark help set the biological clocks for ...

Enzymes known as kinases play a critical role in cell growth, metabolism and signaling in a multitude of organisms across the tree of life—from algae to helminths to mammals. Now, scientists have ...

The second messenger cyclic di-AMP (c-di-AMP) plays a pivotal role in bacterial physiology by regulating osmolyte transport, potassium uptake, cell wall integrity and the overall stress response.