Various fields have struggled with poor reproducibility of studies. A new article in the Journal of the American Medical Informatics Association explores how this issue is affecting the field of ...
Many viruses, particularly RNA viruses, mutate at a very high rate per genome per replication. One possible explanation is that high mutation rates are selected to meet the challenge of fluctuating ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, No. 19 (May 10, 2005), pp. 6819-6824 (6 pages) The use of computers to simulate the functions of complex ...
Jennifer A. Surtees has long been dedicated to studying genome stability and boosting community involvement in research. With a new National Institutes of Health (NIH) grant, she’ll get to do both.
Labs at UC Santa Barbara, UC Berkeley, Stanford and U of Virginia, discovered and replicated 16 novel findings in social-behavioral studies using the best available research practices. Roughly two ...
Roughly two decades ago, a community-wide reckoning emerged concerning the credibility of published literature in the social-behavioral sciences, especially psychology. Several large scale studies ...
Inactivation of mismatch repair (MMR) causes inherited and sporadic cancers 1. These tumours exhibit microsatellite instability (MSI) - length alterations within short repeats. MSI is a diagnostic and ...
Reactive oxygen species (ROS) were long regarded as harmful by-products of mitochondrial metabolism, but growing evidence—including our own—shows that ROS also signal to core processes such as ...
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