A genomic strategy implemented by researchers at Baylor College of Medicine can efficiently increase the molecular diagnostic rate of undiagnosed diseases. The researchers report in the New England ...

When researchers reanalyze patient-level data from randomized controlled trials (RCTs), the trial outcomes change in approximately 1 of 3 cases, according to a study published in the September 10 ...

After more than a decade of controversy surrounding a 2001 clinical trial led by a Brown professor on the effects of the antidepressant Paxil, a reanalysis of the original data claims the drug is no ...

The widely used antidepressant paroxetine is neither safe nor effective for adolescents with depression, concludes a reanalysis of an influential study originally published in 2001. The new results, ...

More than 500 European patients with previously undiagnosed rare disorders received a genetic diagnosis through research carried out by an extensive European collaboration, the Solve-Rare Diseases ...

Study finds significantly lower rates of provider-initiated exome reanalysis among diverse racial, ethnic, and ancestral groups highlighting the importance of proactive reanalysis offerings like Ambry ...

Independent researchers have recrunched a drug company's data for the antidepressant Paxil and reached the opposite conclusion about its safety and effectiveness in children and adolescents. The first ...

The rapid accrual of knowledge in genomic medicine has prompted the reanalysis of existing data. 1,2 We clinically reanalyzed data from two patient series that had undergone diagnostic proband-only ...