Alpha-1 antitrypsin deficiency, or AATD, is an inherited disease that affects the lung, liver, and skin. The current treatment landscape involves smoking cessation, COPD treatment, and augmentation ...

Korro Bio is a biotech company focused on developing RNA editing technology to treat genetic conditions, specifically alpha-1 antitrypsin deficiency. Their most advanced program, KRRO-110, aims to ...

Many writers grouse when an editor makes a change in a story, but the consequences of changing a single word usually aren’t that dire. Not so with genetic instructions for making proteins. Even a ...

Edward M. Kaye, MD, CEO and Director of Stoke Therapeutics. For decades, Adrian Krainer, professor at Cold Spring Harbor Laboratory (CSHL), has studied the mechanisms of RNA splicing, how they go awry ...

Dr. Cech is a biochemist and the author of the forthcoming book “The Catalyst: RNA and the Quest to Unlock Life’s Deepest Secrets,” from which this essay is adapted. From E=mc² to splitting the atom ...

Thomas Gingeras did not intend to upend basic ideas about how the human body works. In 2012 the geneticist, now at Cold Spring Harbor Laboratory in New York State, was one of a few hundred colleagues ...