Symptomatic CPPD disease (formerly known as “pseudogout”) is more common in older than younger adults and typically affects joints with previous damage. Chondrocalcinosis visible on radiographs ...

Inositol pyrophosphates (such as IP7 and IP8) are multifunctional signaling molecules that regulate diverse cellular activities. Inositol pyrophosphates have 'high-energy' phosphoanhydride bonds, so ...

Please provide your email address to receive an email when new articles are posted on . Utilization of pyrophosphate imaging to identify patients with cardiac amyloidosis has increased, although ...

Researchers have discovered two genes, RNF144B and ENPP1, that cause calcium pyrophosphate deposition (CPPD) disease in Americans of European and African descent. This crystalline arthritis is caused ...

In a first-of-its-kind genome-wide association study (GWAS) researchers have discovered two genes, RNF144B and ENPP1, that cause calcium pyrophosphate deposition (CPPD) disease in Americans of ...

Hypophosphatasia results from mutations in the gene for the tissue-nonspecific isozyme of alkaline phosphatase (TNSALP). Inorganic pyrophosphate accumulates extracellularly, leading to rickets or ...

Calcium pyrophosphate deposition (CPDD) disease is characterized by the accumulation of calcium crystals in the cartilage tissues of the joints. The crystal deposits cause inflammation of the affected ...

Many of the modern DNA sequencing techniques involve partially overlapping methods, so our past articles have provided a nice foundation. In this case, the tethered PCR approach that we mentioned in ...

Calcium pyrophosphate deposition disease (CPPD) is a form of arthritis characterised by the accumulation of calcium pyrophosphate crystals within the joint cartilage and surrounding tissues. This ...