This is a preview. Log in through your library . Abstract The phenotypic effect of an allele at one genetic site may depend on alleles at other sites, a phenomenon known as epistasis. Epistasis can ...

This is a preview. Log in through your library . Abstract The evolutionary forces that maintain genetic variation in quantitative traits within populations remain poorly understood. One hypothesis ...

High-throughput sequencing is a rapid form of genomic sequencing that has been extensively used during infectious disease outbreaks, both to track and contain the infection and to monitor for future ...

Some regions of the human genome where the DNA can fold into unusual three-dimensional structures called G-quadruplexes (G4s) show signs that they are preserved by natural selection. When G4s are ...

A novel iLDS statistic uncovers adaptive gene sweeps in gut bacteria, highlighting evolutionary responses to modern diets and enhancing microbiome studies.

That concept was so powerful that we might assume evolution is all about adaptation. So it can be surprising to learn that for half a century, a prevailing view in scholarly circles has been that it’s ...