High-resolution structures of nascent polypeptide chains in complex with the ribosome — the cell’s protein-synthesis machinery — reveal how the ribosome guides protein folding. Ribosomal attachment ...

Protein folding is a critical process by which linear chains of amino acids adopt specific three‐dimensional conformations essential for biological function. In recent years, studies have increasingly ...

Scientists discovered a role played by ribosomes during the folding of new proteins in cells. Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in ...

The latest short science news items from C&EN. Proteins are vital for life, involved in virtually every biochemical process that makes life possible. They comprise one or more amino acid chains ...

When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...

For those outside the chemistry cognoscenti, the announcement might have seemed little more than researchers patting each other on the back. But the question of protein folding had plagued scientists ...

Proteins are long molecules that must fold into complex three-dimensional structures to perform their cellular functions.

New computer simulations that model every atom of a protein as it folds into its final three-dimensional form support the existence of a recently identified type of protein misfolding. Proteins must ...

Edited by: James Kling K.A. Dill, S. Bromberg, K.Z. Yue, K.M. Fiebig, D.P. Yee, P.D. Thomas, H.S. Chan, "Principles of protein-folding-a perspective from simple exact ...

An AI approach developed by researchers from the University of Sheffield and AstraZeneca, could make it easier to design proteins needed for new treatments. In their study published in the journal ...