The application of single-molecule force spectroscopy has revolutionised our understanding of protein folding and intermolecular interactions by allowing the direct interrogation of folding pathways ...

DNA origami cages constrain individual proteins toward preferred orientations on electrodes, dramatically improving ...

Synaptic dysfunction heralds cognitive and behavioral decline in neurodegenerative conditions such as Alzheimer’s and Parkinson’s diseases. Oligomers of Aβ, tau, and ɑ-synuclein may be to blame, but ...

An interdisciplinary team of University of Tennessee, Knoxville researchers recently published in Biophysical Journal on ...

Using high-speed atomic force microscopy (HS-AFM), the Kanazawa University team led by Mikihiro Shibata filmed the dynamic movements of CaMKII at the single-molecule level. The images revealed that a ...

Researchers identify a shared RNA-protein interaction that could lead to broad-spectrum antiviral treatments for ...

In the rapidly advancing field of computational biology, a newly peer-reviewed review explores the transformative role of deep learning techniques in revolutionizing protein structure prediction. The ...

A team at Massachusetts General Hospital uncovered that an immune defense protein, Resistin-like molecule gamma, attacks heart cells after a heart attack—literally punching holes in them. This ...

In a decades-long effort, researchers have discovered how to tweak the molecular pathways that turn heart muscle motors up or down ...

Water trapped inside tiny molecular cavities behaves in a surprisingly energetic way, pushing outward like people crammed in an elevator. When a new molecule enters these narrow spaces, the confined ...