Cancer cells carry thousands of mutations, but not all mutations are created equal. Some make tumors highly visible to the ...

Researchers have created the first complete map showing how hundreds of mutations in a key cancer gene affect tumor growth.

A University of Massachusetts Amherst scientist has discovered that a mutation in the misfolding protein that causes Parkinson's disease offers protection against another fatal neurodegenerative ...

Researchers have elucidated key steps in the ubiquitin tagging of the mutated huntingtin protein, providing hope for future therapies.

In humans, hundreds of proteins interact in a complex network dubbed the interactome. Those interactions are further complicated when disease-causing mutations are introduced into genes that code for ...

Researchers found that paired pathogenic variants can restore protein function rather than make it worse. This phenomenon ...

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth ...

Despite the end of the pandemic, COVID-19 continues to pose a serious health threat. Most individuals have established robust immune protection and do not develop severe disease but the infection can ...

In a recent study posted to the bioRxiv* preprint server, researchers assessed the effects of N501Y mutation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein on ...

A University of Massachusetts Amherst scientist has discovered that a mutation in the misfolding protein that causes Parkinson’s disease offers protection against another fatal neurodegenerative ...