Nature

Monitoring gene expression and amplification through mid-density oligonucleotide array platforms

Array technologies create an opportunity to identify diagnostic and prognostic markers, as well as drug targets, from clinical samples. We have developed a mid-density spotted oligonucleotide array ...
Nature

Oligonucleotide array analysis of telomerase activation by the human papillomavirus type 16 E6 protein

Human papillomavirus type 16 (HPV-16) is strongly associated with the development of cervical cancer. The E6 and E7 proteins from HPV-16 possess several functions that contribute to oncogenesis.
Nanowerk

Microarray Definition: How DNA Microarrays Work, Types, and Uses

Definition: A microarray is a small, flat substrate carrying an ordered grid of microscopic probe features, each containing a known biological molecule, that is used to measure many molecular targets ...
ascopubs.org

Customized Oligonucleotide Microarray Gene Expression–Based Classification of Neuroblastoma Patients Outperforms Current Clinical Risk Stratification

Phase I Study of Adoptive T-Cell Therapy Using Antigen-Specific CD8+ T Cells for the Treatment of Patients With Metastatic Melanoma Two hundred fifty-one neuroblastoma specimens were analyzed using a ...
Nanowerk

Oligonucleotides: Essential Tools in Biotechnology

Therapeutic oligonucleotides act on different stages of pathological gene expression. Standard schematic of oligonucleotide activities in pathogenesis disease progression. Decoys bind to transcription ...
Medical Xpress

Oligonucleotide Array Sequence Analysis

A study led by researchers at King's College London and QIMR Berghofer Medical Research Institute has analyzed genetic data on anxiety symptoms in 693,869 people of European ancestry, revealing new ...