Genome-scale metabolic models (GEMs) cover the entire list of metabolic genes in an organism and associated reactions, in a tissue/condition non-specific manner. RNA-seq provides crucial information ...

The proper use of spike-in normalization in ChIP-seq improves sensitivity for detecting genome-wide changes between conditions, but improper use is common, calling some biological conclusions into ...

It’s tempting just to replicate all databases in the cloud, but it’s a much better approach to get your data house in order as part of the move. Last week I discussed database normalization as a best ...

When normalizing data structures, attributes congregate around the business keys that identify the grain at which those attributes derive their values. Attributes directly related to a person, ...