IDH-mutant glioma, caused by abnormalities in a specific gene (IDH), is the most common malignant brain tumor among young ...

The immune system provides constant surveillance for the body, aiming to spot and eliminate disease-causing microbes or ...

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

Zoldonrasib targets KRAS G12D-mutated non-small cell lung cancer, receiving FDA breakthrough therapy designation for its ...

After decades of fixating on mutations in nuclear DNA as the prime suspects in cancer development, researchers are increasingly peering into the cell’s powerhouse for clues. Mutations in mitochondrial ...

Researchers created a new kind of cancer drug that can grab a mutant protein while also carrying a second hit against the cell.

The study, published in British scientific journal Nature, suggests that the disease may begin in basal stem cells — ...

In Brazil, the early detection of genetic alterations in lung cancer through liquid biopsies could be a valuable tool for ...

KRAS mutations are among the most common genetic alterations in cancer and are considered particularly difficult to treat. In colon cancer, the second most common cause of cancer death, such mutations ...