Formation of the energy-producing machinery in the proximal tubule of the nephron is an essential step in differentiation. The authors show that mitochondrial localization depends on LRRK2, the ...

Cells in culture typically form continuous sheets, like skin. But in 2017, bioengineer Jianping Fu realized that if he cultured human stem cells in a 3D scaffold, they would spontaneously organize ...

Scientists have created a stem cell-derived model of the human embryo in the lab by reprogramming human stem cells. The breakthrough could help research into genetic disorders and in understanding why ...

Researchers have used naïve pluripotent stem cells to create an embryo model that looks and acts like a natural human embryo. They say it’s an ethical way of gaining a better understanding of ...

Genetically-humanized FcRn mice provide translational pharmacokinetics (PK) and pharmacodynamics (PD) data for antibody-based therapeutics. The image illustrates a therapeutic antibody (blue) adhering ...

With the rising technological prowess and greater openness of Chinese models, the world is increasingly turning to the East for efficient and customizable AI, a new report finds.

Inflation and the Covid-19 pandemic have put pharmaceutical productivity front and center in recent years. Thus, drug companies are under mounting pressure to prove that new treatments are safe and ...