The most common genetic cause of hereditary deafness in humans are mutations in the GJB2 gene, especially the 35delG and 235delC mutations. At the recent ARO meeting, researchers from Ear Nose and ...

Researchers restored hearing in preclinical mouse models with a specific form of inherited deafness called DFNA50 caused by mutations in microRNA, by using a novel in vivo CRISPR genome editing ...

Fruit fly models of deficiency in a gene called CPD show defects in Johnston’s organ (JO), a sensory organ on the antennae that helps sense gravity, wind flow, and near-field sound. This confocal ...

For a long time, deafness has often been misunderstood, fueling segregation against people who are deaf or hard of hearing. In some communities, it is still seen as a curse or divine punishment; in ...

The study also looked at safety of the AAV-mediated genome editing approach and found it had a good safety profile that includes little off-target effect and no detectable long-term integration of the ...