The complement system, a central component of innate immunity, exerts a dual influence on cerebral ischaemia, driving both acute tissue injury and later reparative processes. Following arterial ...

The complement system in teleost fish constitutes a cornerstone of innate defence, integrating classical, lectin and alternative activation routes to eliminate pathogens and shape inflammatory ...

Discover how Jules Bordet's Nobel-winning research revolutionized immunology by uncovering the synergy between antibodies and ...

Along with defending against pathogens, the body's innate immune system helps to protect the stability of our genomes in unexpected ways—ways that have important implications for the development of ...

Innate lymphoid cells, which curiously behave like T cells even though they don’t recognize specific antigens, show promise as a potential cancer therapeutic. In the years that followed, other groups ...

Along with defending against pathogens, the body's innate immune system helps to protect the stability of our genomes in unexpected ways -- ways that have important implications for the development of ...

Unlike transient innate immune activation, trained immunity is characterized by long-lasting but reversible functional reprogramming of monocytes, macrophages, natural killer (NK) cells, and ...

Scientists generally agree that eukaryotes, the domain of life whose cells contain nuclei and that includes almost all multicellular organisms, originated from a process involving the symbiotic union ...

Researchers have shown that innate immune training, also known as trained immunity (TRIM), leads to aggravated bone loss in experimental models of periodontitis and inflammatory arthritis. Clinical ...