According to Blakely, unlike the sharp rise in dopamine that triggers euphoria and can lead to addiction, dopamine that dribbles out through a leaky transporter makes it hard for a receptive brain ...

Parkinson's disease is a progressive neurodegenerative disorder that affects more than one million people in the United ...

A new study published in the journal Movement Disorders offers hope for detecting the disease earlier. Scientists used brain ...

With the help of a tiny, transparent worm called Caenorhabditis elegans, researchers have identified novel players in dopamine signaling by taking advantage of a powerful platform generated via the ...

Researchers have discovered a potentially safer yet effective treatment for multiple disorders that display altered dopamine signaling. The “key?” A molecule that targets a specific protein called the ...

The dopamine transporter (DAT) is integral to the regulation of synaptic dopamine levels, a process central to the maintenance of normal neurological function. DAT not only mediates the reuptake of ...

Dopamine, a powerful brain chemical and neurotransmitter, is a key regulator of many important functions such as attention, experiencing pleasure and reward, and coordinating movement. The brain ...

For the first time, researchers are able to describe how the dopamine transporter involved in cocaine use operates at the molecular level, which could pave the way to future targeted treatments.

Methamphetamine addiction has a way of looping back on itself. A rush of pleasure pulls you in, cravings follow, and the ...

Dopamine is the brain's motivational spark, driving us to chase what feels good, say scrolling another reel on social media, and steer clear of what doesn't, like touching a hot stove. But scientists ...

Dopamine doesn’t flood the brain as once believed – it fires in exact, ultra-fast bursts that target specific neurons. The discovery turns a century-old view of dopamine on its head and could ...