- Research published in Molecular Cell used INDUCE-seq to identify DNA topology as an important regulator of CRISPR targeting specificity - Peer-reviewed data demonstrates the sensitivity of ...

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

Inside cells, DNA twists and coils itself into a variety of different secondary structures—including i-motifs (iMs) and ...

It's a common storytelling trope: the stubborn foe who is eventually revealed to be a much-needed friend. Biology has its own ...

When does DNA behave like sand or toothpaste? When the genetic material is so densely packed within a virus, it can behave like grains of sand or toothpaste in a tube. That's essentially what ...

Human life hinges on the ability of our cells to cram six feet of DNA into a 10-micron nucleus -- equivalent to fitting a mile of string inside one green pea. But stuffing genes into cramped quarters ...

Bioengineers have turned a book into DNA. The researchers also have shown they can decode the DNA to re-create the book, which includes 53,426 words, 11 images and one interactive Javascript app. This ...

Broken String Biosciences (“Broken String”), a genomics company building a technology platform to drive the development of cell and gene therapies that are safer by design, today announced that its ...