DNA coding theory bridges the disciplines of mathematics, computer science and molecular biology by applying advanced algebraic and combinatorial techniques to the design of nucleotide sequences. This ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

Decades of research has viewed DNA as a sequence-based instruction manual; yet every cell in the body shares the same genes – so where is the language that writes the memory of cell identities?

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

Artificial intelligence has just redrawn the map of our genome’s control room, revealing hundreds of thousands of tiny DNA ...

(L to R) Co-first author Jackson Mobley, PhD, corresponding author Daniel Savic, PhD, and co-first author Kashi Raj Bhattarai, PhD, all of the St. Jude Department of Pharmacy and Pharmaceutical ...