Common pain relievers may raise heart disease and stroke risk, doctors warn

Common OTC painkillers like ibuprofen may increase heart attack and stroke risk. Learn which medications pose the greatest cardiovascular danger.
Medscape

Risks versus Benefits of Cyclooxygenase-2-selective Nonsteroidal Antiinflammatory Drugs

Am J Health Syst Pharm. 2006;63(19):1837-1851. In a meta-analysis comparing etoricoxib with naproxen, diclofenac, and ibuprofen, etoricoxib was associated with less clinical GI toxicity (perforation, ...
Kitsap Sun

Use caution with pain relievers, even when they come over-the-counter

When people think of harmful pain medications, opioids are often the first drugs that come to mind. The damage these medications can cause has been the topic of news segments, magazine articles, and ...
Medscape

Efficacy and Tolerability of Meloxicam, a COX-2 Preferential Nonsteroidal Anti-Inflammatory Drug

Meloxicam is an enolcarboxamide with preferential COX-2 inhibitory activity. In vitro studies with human tissues have confirmed the high affinity of meloxicam for COX-2, whereas COX-1 was inhibited ...