B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME). Their anti-tumor functions include recognizing tumor-associated antigens, ...

A detailed new map of the human kidney revealed a previously unrecognized form of diabetic kidney disease (DKD) marked by clusters of immune cells—specifically B cells—that are linked to faster ...

Diabetes mellitus affects more than 500 million people worldwide, and both Type 1 (T1D) and Type 2 (T2D) forms converge on a common endpoint: the loss or ...

A multinational collaboration co-led by the Garvan Institute of Medical Research has uncovered a potential explanation for why some cancer patients receiving a type of immunotherapy called checkpoint ...

B cells are white blood cells that form a core part of the body's adaptive immune system, enabling it to recognize specific ...

Kidney damage is a serious complication affecting individuals with lupus, an autoimmune disease where immune B cells ...

Diffuse large B-cell lymphoma (DLBCL) stage 4 is an advanced cancer. Despite its aggressive nature, DLBCL usually responds well to treatment, and new therapies are being developed to help improve ...